PRInnovation GmbHLeipzigTED
MRT-Studie zur Untersuchung von Hirnvolumen bei Patienten mit kognitiven Beeinträchtigungen oder leichter Alzheimer-Demenz
PRImus-AD is a Phase II clinical trial investigating the efficacy and safety of an innovative drug in patients with mild cognitive impairment or mild Alzheimer's dementia. The study is randomised, double-blind, and placebo-controlled with three parallel study arms (two verum arms and one placebo arm). The aim of the clinical trial is to e...
Clinical Trials
No credit card · Instant access
Content at a glance
- Tender type:
- Tender
- Contracting authority:
- PRInnovation GmbH
- Published:
- August 06, 2026
- Deadline:
- Not specified
- Topic:
- Clinical Trials
Tender description
Show full descriptionCollapse description
PRImus-AD is a Phase II clinical trial investigating the efficacy and safety of an innovative drug in patients with mild cognitive impairment or mild Alzheimer's dementia. The study is randomised, double-blind, and placebo-controlled with three parallel study arms (two verum arms and one placebo arm). The aim of the clinical trial is to examine the effects of the active ingredient on neurotoxic protein structures and to evaluate the potential influence on disease progression. Randomised patients were treated for a minimum of 48 weeks up to 96 weeks. A total of 304 patients were divided into the three different treatment arms. An important read-out of the study is the analysis of magnetic resonance imaging (MRI) data to record changes in brain volume at both the individual and group levels. All MRI scans are generated using the same imaging protocol, T2* gradient echo, and diffusion weighted sequences. The study will be conducted in accordance with international standards for good clinical practice (ICH-GCP) and strict quality management guidelines. The schedule provides for a step-by-step evaluation, including the transfer and backup of image data, analysis, and final data
Further details
With free access, documents, deadlines and submission notes are available in a structured format.
- Core requirements of the tender prioritized and prepared
- Deadlines, eligibility criteria and documents in one workflow
- Guidance for structured bid preparation
- Automatically discover matching follow-up tenders
30 days free · no credit card · cancel anytime
All procurement details
Buyer, lots, participants, locations, documents, and procedure data have already been captured. Open any area to see the complete information in your workspace.
7 data areas available
30 days free · no credit card · cancel anytime
Documents
Unlock50 details capturedDocuments · Document bundle
Buyer
Unlock3 details capturedBuyer · Address · Contact
Lots
Unlock1 detail capturedLots LOT-0001
Procedure data
Unlock6 details capturedPublication number · Procedure reference · Buyer reference · Procedure type · +2 more
Performance locations
Unlock2 details capturedPerformance locations
Bidders and contractors
Unlock3 details capturedBidders and contractors · Address · Contact
Publisher
Unlock6 details capturedPublisher · Address · Contact
Related tenders
7MRI substudy
PRInnovation GmbHLeipzigPRImus-AD is a Phase II clinical trial investigating the efficacy and safety of an innovative drug in patients with mild cognitive impairment or mild Alzheimer's dementia. The study is randomised, double-blind, and placebo-controlled with three parallel study arms (two verum arms and one placebo arm). The aim of the clinical trial is to examine the effects of the active ingredient on neurotoxic protein structures and to evaluate the potential influence on disease progression. Randomised patients were treated for a minimum of 48 weeks up to 96 weeks. A total of 304 patients were divided into the three different treatment arms. An important read-out of the study is the analysis of magnetic resonance imaging (MRI) data to record changes in brain volume at both the individual and group levels. All MRI scans are generated using the same imaging protocol, T2* gradient echo, and diffusion weighted sequences. The study will be conducted in accordance with international standards for good clinical practice (ICH-GCP) and strict quality management guidelines. The schedule provides for a step-by-step evaluation, including the transfer and backup of image data, analysis, and final dataGALW/COSE1847/26 Conducting technical and pre-clinical research and development of a novel cardiovascular medical device.
University of Galway (ID 1400)GalwayDeadline: Aug 25The University of Galway are developing a novel technology for supporting the right ventricle during periods of pressure overload. The team are seeking tenders for two different lots of services: Lot 1: R and D Consultant to provide services in the development of a novel cardiovascular medical device for evaluation in a pre-clinical study. Lot 2: The tenderer will offer services for the evaluation of a novel cardiovascular medical device in a large animal model. This contract will involve the development of a protocol and study strategy. The study will include implanting prototype devices in acute animals to demonstrate proof of concept, as well as implanting animals for acute evaluation to support assessment of the prototypes.View CfT Workspace
University of Galway (ID 1400)Deadline: Aug 06The University of Galway are developing a novel technology for supporting the right ventricle during periods of pressure overload. The team are seeking tenders for two different lots of services: Lot 1: R and D Consultant to provide services in the development of a novel cardiovascular medical device for evaluation in a pre-clinical study. Lot 2: The tenderer will offer services for the evaluation of a novel cardiovascular medical device in a large animal model. This contract will involve the development of a protocol and study strategy. The study will include implanting prototype devices in acute animals to demonstrate proof of concept, as well as implanting animals for acute evaluation to support assessment of the prototypes.The provision of smoke movement analysis in flats with unventilated lobbies - July 2026
Department of Housing Local Government and HeritageWexfordDeadline: Aug 14The provision of fire engineering (computer simulation of smoke movement) analysis from an individual flat to common areas, in a building containing flats. The purpose of the study is to determine the likely movement of smoke within the common areas of the notional building. For the analysis of smoke movement within common areas, a simplified layout is provided. Designs are based on the minimum standards specified under TGD B 2024.Update of the European Startup and Scaleup Scoreboard
European Innovation Council and SMEs Executive Agency (EISMEA), EISMEA - European Innovation Council and SMEs Executive AgencyBrusselsDeadline: Aug 11The aim of this action is to update the common methodology and indicator framework of the ESSS 2026 for the collection of data and analysis of startups, scale-ups and their ecosystem in the European Union. This action provides the basis for a regular update of the European Startup Scoreboard to monitor, measure and benchmark the innovation performance of the EU’s start-up ecosystem.Request for Tenders for the provision of an Independent Evaluation of the Small Schools Action Research Project
Department of Education and YouthDublin 1The small schools action research project (SSARP) which falls under the remit of the Department of Education and Youth (DEY) has been in operation since January 2022 and is due to conclude at the end of this school year (June 2026). This project aims to encourage small schools to cluster together in local groups, enabling them to collaborate and identify common challenges and trial innovative solutions. The clusters have been asked to self-identify areas in which they wish to collaborate and identify possible solutions to some of the challenges they face. The focus of their work is the sustainability of small schools and they are currently implementing project work in this area. The DEY invites tenders from suitably qualified and experienced persons to deliver a final independent evaluation of this action research project and to provide an understanding of the impact of the implementation and outcomes of the project that will help inform the future policy development for small schools and their long-term sustainability.Evaluation of the collaboration project Sustainable sick leave
Arbeids- og inkluderingsdepartementetOsloDeadline: Sep 29The Collaboration Project Sustainable Sick Leave (BS) is a part of AID ́s work on following-up the Contract for reduced sick leave and loss from working life (the IA agreement). The collaboration project is anchored in the national budget (Chapter 601, item 75 Enclosed for effective sick leave) and annual awards from AID to the Norwegian Medical Association. The contracting authority would like, with the procurement, to implement an evaluation project that shall be both directed towards mapping the effects/results of the initiatives in the collaboration project BS, at the same time as it is relevant to map and assess the efforts and activities in the cooperation project. Reporting along the way shall contribute to adjusting the measures. The procurement is related to work with following-up sick leave and particularly the interaction between the gp and patient. The collaboration project shall strengthen the GP's role in sick leave work and increase health competence of the population. The project involves implementing initiatives aimed at both general practitioners and patients. The measure includes both awareness raising and training measures aimed at their gp about their sick leave practice and measures to increase patients' awareness and understanding of sick leave. The aim is that cooperation between doctor and patient on sick leave shall be better, and thus contribute to fewer, shorter and better adapted sick leave, including increased use of graded sick leave. There is a need for knowledge that maps the activities in the collaboration project, on the initiatives will be assessed as relevant in the consultation with the sick leavers, whether the measures have an effect on their gp's sick leave practice and if their GP finds that cooperation with registered sick leave, employer, the Norwegian Labour and Welfare Administration has improved and their role and responsibilities in follow-up sick leave has become clearer. There is also a need for knowledge on the collaboration project has contributed to reduced sick leave. The collaboration project is a development project where feedback can be given during the process (evaluation of the process). Based on acquired knowledge on and dialogue with the collaboration project, there is a need to procedural assistance with assessing whether the cooperation project should adjust to the approaches and the activities in the project. See annex 1 of the contract for further details on the delivery.
Frequently asked questions about this tender
- How can I apply for this tender?
- Create a free account on Auftrag One. You will then see all documents, deadlines and submission notes in a structured workflow.
- What is the submission deadline?
- No specific submission deadline is currently stated for this notice.
- Who is the contracting authority?
- The contracting authority is PRInnovation GmbH.
- Which documents are needed to get started?
- Typically you need the service description, proof of eligibility, deadline notes and possibly form sheets. On Auftrag One these items are displayed in prioritized order.